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Multi detector mass spectrometer and spectrometry method filter

專利號
US10867780B2
公開日期
2020-12-15
申請人
Thermo Fisher Scientific (Bremen) GmbH; The University of Bristol(DE Bremen GB Bristol)
發(fā)明人
Johannes Schwieters; Timothy Richard Elliott; Christopher David Coath
IPC分類
H01J49/28; H01J49/02; H01J49/00; H01J49/10
技術(shù)領(lǐng)域
mass,collision,ion,ions,quadrupole,cell,faraday,in,analyser,filter
地域: Bremen

摘要

The present invention can be directed to a mass spectrometer, relevant parts thereof like replacement kits or upgrading kits and/or mass spectrometry methods. A mass spectrometer according to the present invention can comprise at least one ion source for generating a beam of ions from a sample. Moreover at least one mass filter downstream of the ion source can be provided and adapted to select ions from the beam by their mass-to-charge ratio (m/z). Furthermore at least one collision cell arranged downstream of the mass filter can be arranged. At least one sector field mass analyser arranged downstream of the collision cell can be further provided and at least one ion multicollector comprising a plurality of ion detectors arranged downstream of the mass analyser, for detecting a plurality of different ion species in parallel and/or simultaneously.

說明書

In the following, exemplary embodiments of the invention will be described, referring to the figures. These examples are provided to provide further understanding of the invention, without limiting its scope.

In the following description, a series of features and/or steps are described. The skilled person will appreciate that unless required by the context, the order of features and steps is not critical for the resulting configuration and its effect. Further, it will be apparent to the skilled person that irrespective of the order of features and steps, the presence or absence of time delay between steps, can be present between some or all of the described steps.

Referring to FIG. 1 an example of a setup of the present invention is shown. Mass spectrometer 1 is shown with the mass spectrometer 1 optionally having a triaxial ICP torch 10. A sampler cone 11, one (or more) skimmer cone(s) 12, an extraction lens 13 and/or a further skimmer cone 14 and/or another ion optical device 14 can also be present in order to provide the ICP ion source such that a collimated ion beam can be produced by the ion source.

A mass filter 20, such as a quadrupole 20, can be arranged directly downstream the elements mentioned before. Downstream the mass filter 20 a collision cell 30 can be arranged, which may be a HCD (high energy dissociation) cell, which can be heated up to 100-200° C.

After the ions have passed through the collision cell an accelerator 40 can accelerate them to high voltage to be focused into the ion optics of a double focusing high resolution multicollector mass spectrometer to allow for simultaneous measurement of multiple isotopes and/or some monitoring species.

權(quán)利要求

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