The emitter 20e, as the ion source, can be positioned to provide for a relatively compact footprint. As shown in
In some embodiments, the internal distance, from the end of the device 15 defining the internal inlet 15i, can be closely spaced apart from the entry of the mass analyzer 30, to define an internal ion-source to mass analyzer ion entry distance that is between about 1 mm and about 50 mm, between about 1 mm and 40 mm, between about 1 mm and 30 mm, between 1 mm and 20 mm or between about 1 mm and 10 mm. The distance can increase and/or maximize ion transmission without requiring complex ion optics.