Electrospray ionization interface to high pressure mass spectrometry and related methods
摘要
說明書
Only a portion of the fluidic microchip may reside in the vacuum chamber with the mass analyzer.
The ESI device can be configured to electrospray ions into the spatial region external to the vacuum chamber at atmospheric pressure adjacent the inlet device and the at least one emitter can be spaced apart from an end of the inlet device that is external to the vacuum chamber by a distance between about 1-10 mm.
The ESI device can be configured to electrospray ions into the spatial region external to the vacuum chamber. The system can include direct current (DC) power supply connected to the inlet device at a location that is external to the vacuum chamber.
The system can include a power supply configured to apply electrokinetic inputs to the ESI device during operation and a vacuum pump in communication with the vacuum chamber with the mass analyzer.
The mass analyzer can include an ion trap with an injector endcap electrode, a ring electrode and an ejector endcap electrode. The vacuum chamber with the mass analyzer can be held at a gas pressure of between 100 mTorr and 10 Torr during operation.
The inlet device can have an external conical shaped tip with at least one inlet aperture.
The at least one emitter can be spaced apart from an entrance aperture of the mass analyzer a distance of between 1-10 mm.
The system can include a tube or ion funnel electrode assembly in the vacuum chamber with the mass analyzer.
