Each of IHS racks 100A-C has attached respective top panel 230A-C and respective first side panels 131, 141, 151 (see FIG. 1) that encloses at least a portion of IHS racks 100A-C. Upper cable guides 150A-C include support assembly 240 and cable trays 242. In at least one embodiment, support assembly 240 is attached or suspended from a ceiling of data center 120. One cable tray 242 is mounted to the front of support assembly 240 and another cable tray 242 is mounted to the rear of support assembly 240. Cable trays 242 can support, retain and route various power and data cables to IHS racks 100A-C.