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Systems and methods for encoding image features of high-resolution digital images of biological specimens

專利號(hào)
US11176412B2
公開日期
2021-11-16
申請(qǐng)人
Ventana Medical Systems, Inc.(US AZ Tucson)
發(fā)明人
Yao Nie
IPC分類
G06K9/00; G06K9/62; G06T7/11; G06K9/46
技術(shù)領(lǐng)域
superpixel,image,clustering,centroid,clusters,in,cluster,vectors,vector,biological
地域: AZ AZ Tucson

摘要

An image analysis system for analyzing biological specimen images is disclosed. The system may include: a superpixel generator configured to obtain a biological specimen image and group pixels of the biological specimen image into a plurality of superpixels; a feature extractor configured to extract, from each superpixel in the plurality of superpixels, a feature vector comprising a plurality of image features; a clustering engine configured to assign the plurality of superpixels to a predefined number of clusters, each cluster being characterized by a centroid vector of feature vectors of superpixels assigned to the cluster; and a storage interface configured to store, for each superpixel in the plurality of superpixels, clustering information identifying the one cluster to which the superpixel is assigned. The system may also include a graph engine configured construct a graph based on the stored information, and use the graph to perform a graph-based image processing task.

說明書

In order to perform an image processing task using compressed (encoded) data, image analysis system 100 may use storage interface 113 to obtain, for each superpixel, clustering information identifying the cluster to which the superpixel belongs, and then use that that cluster's centroid vector instead of the superpixel's feature vector. Because the clustering algorithm ensures that all superpixels in a given cluster are relatively similar, the centroid vector of the cluster can be a sufficiently good approximation of the feature vector of each superpixel in the cluster, and the greater the number of clusters used, the better the approximation can be.

As discussed above, some image processing tasks rely solely on the distance between two superpixels, i.e., the distance between the superpixels' feature vectors. Such tasks can approximate the distance between superpixels by using the distance between centroid vectors of the two clusters to which the superpixels have been assigned. The distance can be calculated in real time based on the centroid vectors, if the centroid vectors have been stored. Alternatively, the distance can be obtained directly (without additional calculations) from a table or another data structure, if the distances have been precalculated and stored, as discussed above.

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