In an embodiment of the present disclosure, for example, the alignment between the display substrate and the cover plate can be performed in such a way that an alignment device acquires a center of the display region of the display substrate and a center of the display region of the cover plate. For example, as illustrated in FIG. 4, the cover plate 30 includes a transparent window portion 32 located in the display region and a light shielding portion 31 (such as ink and other light shielding materials) located outside the display region to shield structures in the frame region, so as to prevent the structures in the frame region from being seen by users, and an inner edge 31A of the light shielding portion 31 is located at the edge of the display region. The orthographic projections of the plurality of cover plate alignment marks 14 on the base substrate 11 are located in a region where an orthographic projection of the light shielding portion 31 on the base substrate 11 is located. For example, upon light irradiating the display panel, the alignment device can calculate the center of the display region of the display substrate 10 according to the plurality of cover plate alignment marks 14 included in the display substrate 10, and the alignment device can calculate the center of the display region of the cover plate 30 according to the edge 31A of the display region. The alignment device can achieve the alignment between the display substrate 10 and the cover plate 30 by aligning the center of the display region of the display substrate 10 with the center of the display region of the cover plate 30.